Human Fibroblast-Like Synoviocytes (HFLS-RA) Cell Line-Rheumatoid Arthritis

The HFLS-RA cell line consists of primary human fibroblast-like synoviocytes (FLS) derived from the synovial tissue of patients with Rheumatoid Arthritis (RA). These cells serve as a robust in vitro model for studying joint inflammation, cartilage degradation, and autoimmune pathogenesis associated with RA.

HFLS-RA cells display key pathological characteristics of activated synoviocytes, including pro-inflammatory cytokine production, matrix metalloproteinase (MMP) secretion, and invasive behavior, making them invaluable for arthritis drug discovery, cytokine signaling research, and therapeutic screening.

Each vial contains one frozen aliquot of high-viability cells, ready for culture expansion and experimentation.

Applications:

• Rheumatoid arthritis pathogenesis studies
• Cytokine and signaling pathway analysis
• Anti-inflammatory drug screening
• Synovial tissue biology and cellular response modeling

Specifications:

• Cell type: Human fibroblast-like synoviocytes (HFLS)
• Disease origin: Rheumatoid arthritis
• Format: One frozen vial
• Use: In vitro research only