KP-457 (selective ADAM17 inhibitor, CAS# 1365803-52-6), Purity 98% - 25 mG.

KP-457 is a potent and selective inhibitor of ADAM17 (A Disintegrin and Metalloproteinase 17), an enzyme involved in cytokine shedding, TNF-α release, and inflammatory signaling. It is widely used in biochemical, pharmacological, and cancer research to study ADAM17-mediated pathways and therapeutic target validation.

This high-purity compound (≥98%) is ideal for in vitro assays, cellular studies, and drug discovery research related to inflammation, neurodegeneration, and oncology.